Volume 4, Number 4, pp. 219-220
On the energies of hydrogen bonds in a water-bridged collagen structure
I.R. Mesropyan1 and T.V. Burjanadze2
E. Andronikashvili Institute of Physics, Georgian Academy of Sciences, 6 Tamarashvili Street, 0177 Tbilisi, Georgia
2 A. Natashvili Institute of Experimental Morphology, Georgian Academy of Sciences, 2 Chiaureli Street, 0159 Tbilisi, Georgia
An attempt at estimating the energy of hydrogen bonds formed by water molecules in the second triplet position was made on the basis of comparison of the thermodynamic denaturation enthalpies of collagens with different hydroxyproline (Hyp) contents and collagen-like peptides (Pro-Hyp-Gly). It was shown that the binding energy in the first and second positions is equal to 6.5 ± 0.5 kJ/mol.
Keywords: collagen-like peptides, denaturation enthalpy, hydrogen bond, water bridge structure
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